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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '535cfe50753100b7c3d04a0bd3491a71ec35bbae3a86409c4e22d1db40125030' 
  AND token = '6Qgmi6qFFqv/RrgLqFaYyKh/vTQXfeIehCu+oLst6JE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}