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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e062b891b8a22344fe63ef8f1aa1a3f1e5329f05d82043bb5a6a908333a98b' 
  AND token = 'zBBJqvxeCwDTlk66o8atyA+BPmydkREq4z4VuBBwJBI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}