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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '118584300c25b74e6454b35cca3c0774c38558050470088c8f6c4ccbc49488c0' 
  AND token = 'PWsimd/IzAiFsUW1eO9T5B2hAPPP8i7X6feFRhDSnt8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}