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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af3c6646a4b0b3a07d747b4b93207a44536a68e9bcf7eaed4559d0d220d91ecd' 
  AND token = '0jULKj9HuJck2XX65NAcllh0eDvulMMt1hUiySR5Hl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}