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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f0de9b47f489ed94c33a48c748e64857b58c849ea13acc97e16ee7224a7f768' 
  AND token = 'HgMmQlxIhQcFYe9VV0T78KwW2oBJd7AEc5pi5Y4Y/P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}