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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd0fd23e446bb76c23a22f3b31cc649c57c4aa888f1b18bc9e094dc16456f941' 
  AND token = 'uy+GRBThFrKM8ByeAnZQuLfRBohjJMTiKvWcMhn6NNM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}