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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '39e7a96059210b77fc08dbf7750e5da91134a1b80a53ed2f92a61442bfa94144' 
  AND token = 'H6dPL+w5NAj93EdF1dDTUKrenOzjKtRr7LIKfqIN1ZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}