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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1745276aec66f707b0285e42cdc2e0e578b25dd57f18355148a8001ea34a7a1f' 
  AND token = 'sZtJ4iz4YkUHwDhw/HN1+nTrh6sZDDOY4QqR7Xitqpo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}