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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '203485476f15b350ca893d0e846343b541ff8f79d718853dc4a491b5d7f75b70' 
  AND token = 'mDUJ7cWBaHsI1zRaLPSo5KAXRKcCVoHZj1p1eIvAtxk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}