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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75c94428f8b123ba34810b40b2d80e782109a3057cf0c6c5389423e2a815979f' 
  AND token = 'O+NwkN4oYinAsk/4r5YdRIqJi1hdB0ICcPwROOGc0WU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}