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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72424c17772c1dbd0ac17716fbf5f24ac8c3d7a8d98eb42293aee03ae2d0ddd5' 
  AND token = 'ITa30G/1YKKF+VrAmkHA+fCNMcpJ853s/J6uNcQKAvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}