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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2945ca8b175a5ff817939732c9a64bd1d8a39a3a3c541d3f0d5bccdf7ec77b17' 
  AND token = 'JTxaLUno389mTPRxQw3C9gneTlZGQAKt1wzQ/BAUQ2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}