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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37575ec454b2104ff514380d5f7e97f782ceec81249d4b3ddc761f44daafc5a6' 
  AND token = 'aXSTX6RqD3cMrLlPleMha3nV5moC7Pd3FUyBFzmsK9c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}