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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c271cd1b2537b32f7c4763a10233d6cd626bde3bac4b6d13de03b7d95681b45' 
  AND token = 'CSLmqEF+0UHWHhU8a3hLGu4j6NsMR1HoNrSQc9ViJR4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}