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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bdb068af86f9bf8522ed489b7e465a92cdb35832843f07321d0b14f2595f539' 
  AND token = 't2oWqOx/MqTZW1XAOv3t5PvyrsN6BbSOqHnAVquduKc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}