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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c46a5bfe4d52800b943801e0bab255efdb9cc042c99ba72a23dc643f5a1d2d86' 
  AND token = '/LA/guRqnhjyNt0lZwFlXnZOnw0tZ1U2tG9W7Q0DHj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}