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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e80e0db759aae67c0d9303f18bd6544212db73a1e3daef42b04b3472657271f' 
  AND token = '4lebq80QWgxeyRoreT23MHatt1SRnnfGpAJD+67hH2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}