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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffdd155b55642b9d7a2074fc8263f867863f9404eb2f830d3d40f250419f3aa6' 
  AND token = 'EOq7e37cvcKWoZ6LiJGEmQqZFUNA1+7aOFA0fxVQuxs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}