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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '03b64263d61d8d615d75c6ab212e5d1aa877d8a2aaa1c27382b328b0825de2d6' 
  AND token = 'zbSS+1SKdbLrzR0A6QVzRBM7E6VOwk6BhnhBfjGzlBQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}