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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800661400ee89d2a6b6a0b9d6a5c2a7c3cb5f477a72b8a51966beb5628a02f15' 
  AND token = 'hR3+CsA63u+oujV4cVkCD9LY0dKJYxPb/m2IOSdR8eQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}