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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b53d86b287fc254472304e85f957d2662c80be0501b472d5afce1264656d4e8' 
  AND token = 'mAC52Pj58+aClPjJrRhtG/YpLEFgf0xPOgt1ri6vKu0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00009

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}