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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd10973eed9aca1dbb06793f34039de4ddb1d531c35395dafd85af9e0864d4740' 
  AND token = 'E0hJlco0D/lNUmhWFRi/nLDel/IiYo3ZlLkWpD7V8T0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}