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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '200194360537284e29a8b51549af28884805dbd717b92fd8b1b153b4a04f000f' 
  AND token = 'F5HgwwwDQmMAUdaYRNX7HEZkIRqzr/5Qmk8IqzOfh6M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}