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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ded5181e282639a8c88996d094ed9c4e97741654735584266ab11d44e2cfdbd' 
  AND token = 'TLp3njEn8KhwhrUXXJ5NgOXKKd9wOnLpEEFWVWgQMKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}