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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a3487b00b0742717c22a53a1966afc41d78b56a0e7159755e8b57fea764033a' 
  AND token = 'z4J13Ek9fpuTZMtCmMSBryt1wWrBxsmx8Swr3l0I5eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}