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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e21a591b101276faaee087e72255f7d28f17c8509b97f0209596c9b193e4cc6' 
  AND token = 'nj5NyLBSl04tziF++NddpkiDbDezAZoSz8VigwWcAMA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}