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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e7248d7e1d865dd9eb7c59b9f9c44e368e7bdc58fdd7789075a36db99ba9d643' 
  AND token = 'mAmiw1s6Qt5hoAafpSGB+xU4M3GssQ3ZZbFSO+TbzcA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}