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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89e6187900c829db6361892a84abdd440fa93ed757132094a5d88e7bcb8b2285' 
  AND token = '9u6dZKjNr02ZTU6jQgAi0gTa+V43nWF/7VZvm+27vCU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}