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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2d3b218008fa6a227f4cfee6957d712796a672e26d2fd922c3469f37bab5b53' 
  AND token = 'HxcgefBz7XXE65t8Y1ysLS6Bu6MuXLyOa/18NJ/bKII=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}