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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3257ae6c19832d887d5224953c7a85d15acf2525a648a25b5f4b6bb88792518' 
  AND token = '448B+PLIOmWkUhnwXEruUSen3Xqg7LWLL9RRgHAxfnY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}