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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5755ca731452873608bf2a17929c8aab2aa1ec4c00f75590acea3de414c4c786' 
  AND token = 'pxwDVLRTc8OV/FFjZWCS2r7YX+uahA1kWvVZlOdlWao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}