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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0c82e5224b8d5e5d14247b1ec6a788da4bf8dafb26d5b52855d3391e6209800' 
  AND token = 'V8RLk/mNnKBycCHe3DOdM+pJNVIALDQag3DZOF4KijM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}