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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '213895c96fc4f8ef0465873fa85b50b1781a134b8ec570d000c3b92d4fddce9e' 
  AND token = 'bre2XIfLpvJcyUhWVBo2xkAlSF4RT+dXcPcB/8GxmBc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}