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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b27757285f86bbdc6d2c9fc61096bdf3760bcfad78a7ad3ee644742acd2260cd' 
  AND token = 'P0o4anNpHnwPh9XSwfWuSV8Rlvwt0qUzpdnRB3/675Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}