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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7352a795fa75af7303cedacf78c3a5ad6ef6b0d7afede30eb42ccbc058b434d4' 
  AND token = 'xtQ8AFBeHwjlpr1YUy6QH6zWfwy5HXVnO4GCTUuDAmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}