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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cca57a9ac930bb6c5fe90a1214d1f5729431b1812b6394ae63df4caf4bfd793' 
  AND token = 'sMu4u/2+NZM49ayxtCditgIFFxuUatCNXGEmfn3rPgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}