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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '065b8cdc800a52d25fb534030ccf210ae3a13646a3e887355cb7a3cae7d21a41' 
  AND token = 'Tak+EdXFedl9W6isIXADFxfRfF1L1HL1U1jNSXXClSg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}