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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1d60de7d64156668f795b89e4c264bd4f4f5a1c52e0299e059e1082fc104b57' 
  AND token = 'lqo6tsQkCk3M9py/Xc5ISUxy5Vo/QyzTFeKrB7WsHIU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}