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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f7058e3974b7efb97bfe5a8859e3bcc31bf79174185d1996ae075c119ccac55' 
  AND token = 'YruRUwHNNkTmMm5yr8PnSEqLwOyhi8Aj2LZg7tjhZ1U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}