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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8a3ae1c7384c032b233180cbbf221e8a7ed730bde5f4f0822a344e1870f426d' 
  AND token = 'fqO/byC113Sglj7GYSbazZrrnsuAQWxhz+gs1NUNiIo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}