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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0488787fb129e8237ef32a6bdfbc91d492aab9205cb21173b1c206edac1520a8' 
  AND token = 's2UZoQp+5YK2awsEzIhU5KZVZc5800AU2g07wcDU8D4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}