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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec4b91c2697a6a26d47cdfaf3ee03c43d549eec3d9ad8e55c1e2291db35913e7' 
  AND token = '26CoqAx+IsmLWn5Ll6BZbsjLz4zz+EtMsTrLYAz0FC0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}