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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1fb5a1df8430c4b80b52a94f07d9266b835adb7507bfade51515833d1545670' 
  AND token = '2zYolHjWoHzJaIRLYWkob3mTI9VXoQqZxCDaFECSLzc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00008

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}