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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efe07a0c40c705bfbb81c56ab13fbb6ad01404557262de47bac6fc7eff37f480' 
  AND token = 'sAqN1ElHVfDFuh9RINaY07yNZpImjFFU3ZPpLaKDKzM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}