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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ca7b9bfa302d3ad72904b8cdeb59df4047ffe95f95aa2385752f68cae5c9bdc' 
  AND token = 'P2KtXzGOc5baQiYduCZFVNeYn5Za5EjWFxLm4pdA2TM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}