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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd68b77cbb7640bee9e733642a4fb14b9f69415865ef1f2cd0d967f8e69755d0d' 
  AND token = 'UAuirFI4vBi0uiKi+kiIeLosGYhQTyJsXSioqQpf0eI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00012

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}