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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd80cc095eddede00704cb0c32d0b00219abea922f3a0fffb9a48309770f64d17' 
  AND token = 'f7aBKQP7vdziZYv8DjQ10ufm+8Db2q4BhTMEvhJb8Og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}