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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65427e5f09e0812fcb5c110c84490f434012f371beabe2296a97046473cdbfa3' 
  AND token = 'tg4csdqAIFBx1tZQZbkZgHggVx3hk4v2FluNkkKnwjo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00011

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}