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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e97228f84e4034d87d06c8eb12021fd15f722ab859122b30f2112ea661fa12cc' 
  AND token = '+eeIliNtPvns4zJYsERRH72DA+YRcby63AOHHG+DiKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}