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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72f9d624212e348974959df666a9af7979df9782ecd141a6471e1667fbdd3aab' 
  AND token = 'S5vpiHAT5qAAyORev4PU4sBcFUFmCJCEQ3BTlv4AI+o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00010

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}